The simple answer is yes.
The more complicated answer is that there are many things to learn about living and working on the road. Things I wish I had known before I started. That being said, do NOT wait to learn them before you go. You can learn them on the way. You can learn some of them here on this site. You can learn them from other travelers. If you plan, and plan, and plan....you will plan. Life unexpected will happen and you will postpone, postpone, postpone...and you will not go..you will not.
Pick a date. Pick a mode of travel. Disconnect the electricity. Pack your bags and take that first step...then another. I promise you won't regret it.
Your friends and family will worry - they will get over it. You will be afraid - you will get over it.
What you will never get over is the sight of a doe sneaking past your window on a foggy morning or the sunrise over a jagged peak in the Tetons. Your trip through Gettysburg or Pearl Harbor or Auschwitz will bring tears. Your travels to the Lincoln memorial or Niagra Falls or the Grand Canyon or Tikal will fill you with awe.
You will laugh. You will love. You will experience more life than you thought possible and you will feel sorry for the people passing you on the highway on their way to work.